Journal of AdvancedMedical and Dental Sciences Research

Background: Hyperglycemia and inadequate endogenous insulin production and function are two features of diabetes mellitus. The present study was conducted to conducted to assess MDA, creatinine and Cystatin C level in patients with diabetes mellitus. Materials & Methods: 80 diabetic patients of both genders were put in group I and group II had 80 healthy subjects. The level of malondialdehyde (MDA), Cystatin C and creatinine levels were measured in both groups. Results: Group I had 45 males and 35 females and group II had 40 males and 40 females. Cystatin C level was 0.82 mg/L in group I and 0.87 mg/L in group II. MDA level was 4.01 µM in group I and was 1.36 µM in group II. Creatinine level was 0.94 mg/L in group I and 0.85 mg/L in group II. The difference was significant (P< 0.05). Conclusion: There was elevated level of MDA in patients with diabetes mellitus in contrast to normal healthy subjects. Key words: malondialdehyde, Cystatin C, Creatinine.