Journal of AdvancedMedical and Dental Sciences Research

Background: Neonatal sepsis is a systemic infection occurring in infants at 28 days of life and is an important cause of morbidity and mortality of newborns. The present study was conducted to assess clinical outcome of neonatal sepsis. Materials & Methods: 94 neonates diagnosed of neonatal sepsis in both genders were included. Parameters such as antenatal care, duration of labour, gestational age (GA), mode of delivery, total white blood cells, types of antibiotics used etc. was recorded. Results: Out of 94 neonates, boys were 54 and girls were 40. Age of patients was 0-7 days in 50 and 8-28 days in 44, duration of labour was <6 hours in 26, 6-12 hours in 24, 12-24 hours in 30 and >24 hours in 14. ANC was seen in 60, gestational age was pre- term in 64 and term in 30, mode of delivery was vaginal in 70 and caesarean in 24, TWBC count was <5000/ mm3 in 36, 5000-12000/ mm3 in 24 and >12000 /mm3 in 34 patients. The difference was significant (P< 0.05). Type of antibiotic used was Cloxacillin in 15%, Ampicillin+ Gentamicin in 60%, Benzyl Penicillin in 20% and Ciprofloxacin in 5%. The difference was significant (P< 0.05). Conclusion: Boys were affected more than girls. Neonates with sepsis were mostly managed with Ampicillin+ Gentamicin combination.