Journal of AdvancedMedical and Dental Sciences Research

Background: The main challenges in obstetric anaesthesia are selection of the most effective management strategy for SAIH during CS. The present study compared intravenous norepinephrine and mephentermine for maintenance of blood pressure during spinal anaesthesia for caesarean section. Materials & Methods: 80parturients selected for elective caesarean section (CS) under subarachnoid block (SAB) were selected and group I subject received boluses of intravenous 8 µg norepinephrine and group II received 6 mg mephentermine for SAIH. Parameters such as systolic blood pressure (SBP), diastolic blood pressure (DBP), Apgar score and adverse effects were recorded and compared in both groups. Results: The mean age in group I subject was 25.8 years and in group II was 26.1 years, height was 160.2 cm in group I and 162.5 cm in group II, weight was 65.7 kgs in group I and 66.2 kgs in group II, duration of surgery was 48.3 minutes in group I and 49.2 minutes in group II, APGAR score at 1st minute was 7.22 in group I and 7.40 in group II and at 5 minutes was 9.02 in group I and 9.06 in group II. The difference was non- significant (P> 0.05).There was a non- significant difference in change in systolic and diastolic blood pressure in both groups (P> 0.05). Side effects reported were nausea/ vomiting seen 2 in group I and 4 in group II, headache seen 3 in group I and 6 in group II, shivering seen 2 in group I and 2 in group II and hypertension seen in 1 in group I and 2 in group II subjects. The difference was significant (P< 0.05). Conclusion: Intravenous norepinephrine was comparable with mephentermine in maintenance of blood pressure during spinal anaesthesia for caesarean section.