Journal of AdvancedMedical and Dental Sciences Research

Material and Methods: One hundred twenty type II DM patients of both genders were divided into 2 groups of 55 each. Group I comprised of patients with good control HbA1C ≤ 7%. Group II had diabetes mellitus with poor glycemic control HbA1C > 7%. Parameters such as age, height (m), weight (kg), body mass index (BMI) were measured. All the subjects underwent fasting blood sugar level, postprandial blood sugar level, HbA1C, HsCRP (high-sensitivity C-reactive protein), serum ferritin, serum fibrinogen and pulmonary function test such as FVC (forced vital capacity), forced expiratory volume in 1 second (FEV1), FEV1/ FVC, FEV1% (FEV1 as percentage of FVC), PEFR (peak expiratory flow rate), MMEF (maximum mid expiratory rate), SVC (slow vital capacity) were performed. Results: Group I had 40 males and 30 females and group II had 35 males and 35 females. Percentage predicted FEV1 was 100.4 and 80.5, percentage predicted FVC was 102.8 and 72.1, percentage predicted FEV1% was 96.2 and 99.0, percentage predicted PEFR was 114.2 and 92.7, percentage predicted SVC was 82.5 and 74.5 and percentage predicted MMEF was 85.3 and 81.7 in group I and II respectively. The difference was significant (P< 0.05). Conclusion: Pulmonary functions were decreased significantly increased in uncontrolled diabetics.