Journal of AdvancedMedical and Dental Sciences Research

Background: Local anaesthesia continues to be used in many cases of septal and nasal reconstruction surgery. The present study was conducted to evaluate the efficacy of cocaine tetracaine plus adrenaline for patients undergoing septoplasty. Materials & Methods: 60 patients undergoing septoplasty of both genders were divided into 2 groups of 30 each. Group I was in which 5 ml of cocaine 4 per cent solution (200 mg) was used and in group B, in which 5 ml of tetracaine2 per cent solution plus adrenaline was used. VAS and complications occurring during the procedure were recorded. Results: Group I had 20 males and 10 females and group II had 14 males and 16 females. The mean VAS score in group I was 6.2 and in group II was 4.1. The difference was significant (P< 0.05). Adverse events recorded were CNS restlessness in 4 in group I and 2 in group II, bradycardia 2 in group I and 1 in group II and tachycardia 1 in group I. The difference was significant (P< 0.05). Conclusion: Tetracycline found to be better as compared to cocaine in terms of less pain score and adverse events.