Journal of AdvancedMedical and Dental Sciences Research

Background: Diabetes mellitus (DM) has been recognized as a ‘prothrombotic tendency’ with increased platelet reactivity. The present study was conducted to assess platelet indices in diabetics and healthy subjects. Materials & Methods: 120 cases of diabetes mellitus of both genderswere put in group I and healthy control in group II. 5 mlvenous blood were drawn from the antecubital vein and immediately mixed in EDTA vacutainers. The platelet indices such as MPV, PDW and P-LCR was determined in both groups. Results: Out of 120 patients, males were 70 and females were 50. The mean MPV in group I was 12.6 fl and in group II was 9.1 fl, PDW was 14.8 fl in group I and 10.6 fl in group II and P- LCR was 34.4% in group I and 25.2% in group II. The difference was significant (P< 0.05). Conclusion: Platelet indices were higher in diabetics in comparison to healthy subjects.