Journal of AdvancedMedical and Dental Sciences Research

Background: Dyslipidaemia refers to abnormalities in blood lipid and lipoprotein levels, has been established as a major modifiable risk factor for cardiovascular disease. The present study was conducted to assess abnormalities in lipid profiles amongst hypertensive patients. Materials & Methods: 82 hypertensive patients of both genders were recruited. Group I consisted of hypertensive patients and group II had healthy control. Systolic (SBP) and diastolic (DBP) blood pressures, body mass index, fasting blood glucose and fasting serum lipid profile was recorded. Results: Group I had 40 males and 42 females and group II had 38 males and 44 females. In group I and II, WC (cm) was 95.4 and 91.4, WHR was 0.99 and 0.95, FBS (mmol/L) was 5.2 and 4.7, TG was 1.27 and 1.12, HDL-c was 1.28 and 1.25, LDL- c was 3.04 and 2.44 and TC was 4.86 and 4.16, SBP (mm Hg) was 160.4 and 118.4, DBP (mm Hg) was 97.4 and 72.2, BMI (kg/m2) was 29.6 and 27.2 respectively. Elevated TC (≥5.2 mmol/L) was seen in 32%and 10%, elevated TG (≥1.7 mmol/L) in 8% and 2%, elevated LDL-C (≥3.4 mmol/L) in 24% and 5%, low HDL-C (<1.04 mmol/L) in 20% and 15%, no lipid abnormality in 52% and 70%, one lipid abnormality in 26% and 18% and >2 lipid abnormality in 24% and 12% in group I and II respectively. The difference was significant (P< 0.05). Conclusion: Lipid parameters were alteredin hypertensive patients as compared to healthy subjects.