Journal of AdvancedMedical and Dental Sciences Research

Background: HAV is one of the major feco-orally transmitted agents and responsible for 1.4 million new cases per year. The present study was conducted to hepatitis A and E viruses in patients of acute viral hepatitis. Materials & Methods: 56 patients of acute viral hepatitis of both genders were enrolled. 5 ml blood samples were collected aseptically. Serum was assessed for anti HAV immunoglobulin M (IgM) and anti-HEV IgM antibodies. All analyses were performed using commercial kits based on the enzyme-linked immunosorbent assay. Results: Out of 56 patients, males were 32 and females were 24.Hepatitis A was seen in 20, Hepatitis E in 25 and Hepatitis A+ E in 11 patients. The clinical features found in Hepatitis A and Hepatitis E was pallor seen in 42 and 40, encephalopathy in 38 and 27, hepatomegaly in 26 and 13 and yellowish discoloration in 52 and 54 respectively. The difference was significant (P< 0.05). Conclusion: Common clinical features found to be pallor, encephalopathy, hepatomegaly and yellowish discoloration.