Journal of AdvancedMedical and Dental Sciences Research

Background: Dengue is an arboviral disease caused by infection with any one of four related dengue virus (DENV) serotypes.The present study was conducted to assess clinico-microbiological findings of dengue fever. Materials & Methods: 84 patients of dengue viral infection of both genders were enrolled. Evaluation of NS1 antigen, IgM and IgG antibodies was done. NS1 antigen and IgM antibodies using ELISA methodand IgG antibodies were detected using lateral flow assay. Results: Out of 84 patients, males were 54 and females were 30. Common symptoms recorded were headache in 57, retro orbital pain in 26, myalgia in 42, arthralgia in 38, rash in 62 and bleeding in 43 patients. A significant difference was observed (P<0.05). NS1 was identified in 42%, IgM in 23%, IgG in 4%, NS1+ IgM in 20%, NS1+ IgG in 4% and NS1+ IgM+ IgG in 7%. A significant difference was observed (P< 0.05). Conclusion: In maximum cases, NS1 was identified followed by NS1+ IgM.