Journal of AdvancedMedical and Dental Sciences Research

Background: Chronic total occlusions (CTOs) are complex lesions identified in 15-30% of all patients referred for coronary angiography. Percutaneous coronary intervention (PCI) of chronic total occlusion (CTO) is one of the major challenges in interventional cardiology. Hence; the present study was conducted for assessing the results of percutaneous coronary intervention for chronic total occlusions of coronary arteries. Materials & methods: A total 50 subjects were enrolled. The study included subjects of all ages and genders, admitted as in patients for PCI and suffering from CTO. The indications for offering PCI intervention to CTO lesions were either clinical symptoms of ischemia, or demonstration of viable myocardium in the absence of symptoms and finally technical feasibility as judged by the operator himself. The femoral approach was followed for opening the CTO in all cases. For wire escalation the Step up approach was used starting with moderate stiffness and increased stiffness as procedure progresses. Left ventricular ejection fraction (LVEF) is the central measure of left ventricular systolic function. All the results were recorded in Microsoft excel sheet and were analysed by SPSS software. Results: Single and double vessel involvement occurred in 36 percent of the patients (18 patients) and 38 percent of the patients (19 patients) respectively. Triple vessel involvement occurred in 26 percent of the patients (13 patients). Primary access site was right femoral and right radial in 64 percent of the CTO lesions and 26 percent of the CTO lesions respectively. Intramural hematoma was seen in 6 percent of the patients while post stenting slow flow was seen in 4 percent of the patients. Coronary dissection was seen in 4 percent of the patients. Conclusion: Percutaneous coronary intervention in chronic total occlusion is an effective therapeutic procedure. So, despite the technical difficulty of PCI in CTO lesion, this procedure can be done safely with relatively significant success rate.