Journal of AdvancedMedical and Dental Sciences Research

Background: In children and adolescents, type 1 diabetes mellitus (T1DM) is the most common endocrine-metabolic disorder, with significant physical and psychosocial repercussions. Those children will require exogenous insulin on a regular basis, as well as the ability to check their own glucose levels and pay close attention to the irnutritiona lconsumption. Magnesium levels may be decreased in patients with type 1 diabetes mellitus (T1DM), influencing disease control. Present study aimed to evaluate association between serum magnesium levels and glycemic management in children withT1DM. Materials and method: A 94 diabetic child with T1DM, and a 30 healthy control of similar ages were involved in this study. Both groups had blood samples drawn to determine serum magnesium and HbA1c levels. Data were statistically analyzed using SPSS 22. A Pvalue of <0.05 was considered significant. Results: The serum magnesium is significantly low among males than females in the diabetic group. Serum magnesium is significantly low in children with T1DMspecially in those with poorly controlled diabetes (high level of HbA1c) in comparison with control group(non-diabetic children). The high prevalence of magnesium deficiency in diabetes mellitus may be due to insufficient dietary intake, or impaired intestinal absorption of magnesium or increased urinary loss of magnesium compared to healthy individuals. Conclusion: Serum magnesium level is frequently low in children with type 1 diabetes mellitus. There is a significant correlation between serum magnesium leveland the glycemic control. Therefore we recommenddoing regular monitoring of serum magnesium in typ 1diabetic childrenand appropriate supplement of low levels.