Journal of AdvancedMedical and Dental Sciences Research

Background: Liver biopsy serves an important role in the definitive diagnosis of liver diseases, determining the grade and stage of the disease and also in evaluating the effect of therapy. It is particularly useful in the diagnosis of biliary atresia. The present study was conducted to assess hepatic lesions. Materials & Methods: 136 liver biopsies were stained with Hematoxylin and Eosin (H&E) and were examined under the microscope. Results: Age group 0-10 years had 1, 11-20 had 12, 21-30 had 20, 31-40 had 25 and >40 years had 10 hepatic lesions. The difference was significant (P< 0.05). Histopathological diagnosis were primary Hepatic Tumour in 5, hepatic Secondaries in11, Cirrhosis in 10, Secondary Biliary Cirrhosis in 4, Viral Hepatitis in 15, Alcoholic Hepatitis in 6, Glycogen Storage Disease in 2, Fatty liver in 14 and Cystic Hydatid Disease in 1 case. The difference was significant (P< 0.05). Conclusion: Histopathological examination of liver biopsy helps to diagnose and assess the severity of various hepatic diseases. Key words: biopsy, Histopathological, liver