Journal of AdvancedMedical and Dental Sciences Research

Background: Hyoscine butyl bromide (Buscopan) is being used as an agent for reducing the duration of labour. There are however conflicting results on the effect of this agent on cervical dilation. The present study was conducted to compare effect of different concentration of Hyoscine Butylbromide on labor. Materials & Methods: The present study was conducted 60 prim gravid women with term gestation. All were divided into 2 groups of 30 each. In group I 40 mg of intra-venous HBB in the early active phase of labor was given and in group II 60 mg of intra-venous HBB was given. Results: Each group had 30 patients each. Group I patients were given 40 mg of intra-venous HBB and group II received 60 mg of intra-venous HBB. The mode of delivery in group I was abdominal seen in 10 and 8 in group II. It was vaginal seen 20 in group I and 22 in group II. The difference was non- significant (P> 0.05). APGAR score at 1st minute in group I was 8.2 and in group II was 8.4, APGAR score at 5th minute in group I was 8.4 and in group II was 8.6. Estimated blood loss in group I was 320 ml and in group II was 350 ml, injection to delivery time in group I was 322 minutes and in group II was 312 minutes, rupture of membranes to delivery was 104 minutes in group I and 120 minutes in group II. The difference was non- significant (P> 0.05). Conclusion: Authors found 40mg HBB and 60 mg HBB found to be efficacious at both concentrations. There was no significant difference in their outcome.