Journal of AdvancedMedical and Dental Sciences Research

Background and Objective: Determining and monitoring the prevalence of ADRs of antidepressant medications in MDD patients in a tertiary care teaching hospital. Materials and Method: Patients prescribed with at least one antidepressant were selected and monitored for adverse drug reactions (ADRs), irrespective of their age and gender. Results : TCAs was the most frequently prescribed antidepressants and most commonly associated with ADRs. Dry mouth and weight gain were the most frequently reported ADRs. Majority of the ADRs were ‘mild’ in their severity. Conclusion: TCAs were the most common antidepressants implicated in causation of ADRs. SSRIs were relatively safer and produced minimal adverse effects. Anticholinergic adverse effects occurred in majority followed by sedation and weight gain effects.