Journal of AdvancedMedical and Dental Sciences Research

Background: Child birth is allied with very severe pain for most women. Acetaminophen is also known as paracetamol, is commonly used for its analgesic and antipyretic effects. Hence; the present study was undertaken for assessing the efficacy of an intravenous infusion of acetaminophen during the active phase of labour. Materials & methods: A total of 100 pregnant females were enrolled. All the subjects were broadly divided into two study groups, with 50 patients in each group, as follows: Group A: Patients received IV Acetaminophen, and Group B: Patients reviving matched placebo. Secondary outcome measures included duration of labour, and VAS. All the results were recorded and analysed by SPSS software. Results: Mean duration of first stage labour among the subjects of the study group and the control group was 386.2 minutes and 663.6 minutes respectively. Significant results were obtained while comparing the mean duration of first stage of labour among study group and the control group of the subjects. Mean VAS after 30 minutes among subjects of study group and control group was 7.82 and 6.46 respectively. Significant results were obtained while comparing mean VAS after 30 minutes among subjects of the study group and the control group. Conclusion: Intravenous acetaminophen is an efficacious non-opioid drug for relieving labour pain and decreasing duration of labour without any significant adverse effects.