Journal of AdvancedMedical and Dental Sciences Research

Background: Liver is an interesting organ with high regenerative capacity and complex functions. Cirrhosis is defined as the histological development of regenerative nodules surrounded by fibrous bands in response to chronic liver injury, that leads to portal hypertension and end stage liver disease. Hence; the present study was undertaken for assessing the demographic and Clinical Profile in Patients with Liver Cirrhosis. Materials & methods: 50 patients suffering from cirrhosis of either sex were enrolled. Physical examination was concentrated to detect stigmata of chronic liver disease like clubbing in fingers and toes, central and peripheral cyanosis, presence of spider angioma, telangiectasia, jaundice, collateral veins in abdomen, ascites, level of consciousness, splenomegaly, dyspnoea, peripheral edema, palmar erythema and pleural effusion for underlying etiology. All the patients were investigated for haematological tests. All the patients were graded according to Child Pugh Score on the basis of increasing severity as follows: Grade A, Grade B and Grade C. Results: Alcohol was the etiologic profile in 62 percent of the patients while NASH and hepatitis C was the etiologic profile in 16 percent and 12 percent of the patients respectively. According to child Pugh score, 58 percent of the patients were of grade B while 22 percent of the patients were of grade C. Conclusion: Liver cirrhosis is more common among adult males with alcohol being the most common etiologic profile.