Categories

Volume 7 Issue 10 (October, 2019)

Original Articles

Assessment of prescription pattern and adverse drug reaction profile of drugs prescribed in dermatology OPD- An observational study
Dr. Sharad Chaddha, Dr. Shailendra Mishra

Background: Skin diseases are common and cause a huge disease burden globally. Adverse Drug Reactions (ADRs) are considered as one among the leading causes of morbidity and mortality. Hence; the present study was conducted with the aim of assessing the prescription pattern and adverse drug reaction profile of drugs prescribed in dermatology OPD. Materials & methods: Over a period a period of 6 months, 1100 patients were analysed. Written consent was obtained from all the patients after explaining in detail the entire research protocol. Analysis of the case sheet of patients was done for prescription pattern using WHO core drug use indicators was done. Simultaneously development of any adverse drug reaction (ADR) to drug prescribed was observed with present visit and follow-up visit after 3 days. Results: Total number of drugs given was 4236 while average number drugs per prescription were 3.85. Percentage of drugs prescribed by generic name was 33.8 while percentage of drugs prescribed by brand name was 66.2. Among the drugs prescribed by oral route, antibacterial comprised of 63.4 percent, antifungal were given in 22.7 percent of the patients. Corticosteroids, Antihistaminic, Multi Vitamins and Gastro-protective drugs were given in 5.9 percent, 94.6 percent, 86.2 percent and 70.1 percent of the patients respectively. Maculo-papular rash was seen in 11 patients. Fixed drug eruption was seen in 9 cases. Conclusion: Non-essential medicines and non-Generic drugs are routinely used. Hence there is a need to stress the prescribers to adhere to the prescription guidelines.

 
Abstract View | Download PDF | Current Issue