Journal of AdvancedMedical and Dental Sciences Research

Background: TRUS-guided prostate biopsy has been preferred as a standard prostate cancer diagnostic method. At least two local anesthesia techniques are currently available during transrectal ultrasound (TRUS)-guided biopsy: local anesthesia with 2% lidocaine gel and periprostatic nerve block. Hence; the present study was undertaken for comparing the efficacy of different local anesthesia techniques during TRUS-guided biopsies. Materials & Methods: A total of 90 patients who were referred for TRUS-guided biopsy for the first time were enrolled in this study. Pains scores were assessed on the grade of 0 to 5 with 0 indicating no pain and 5 indicating unbearable intolerable pain. All the patients were randomized into three study groups: Lidocaine gel: patients in which Lidocaine gel was used topically, Peri-anal block group: Patients in which peri-anal block was used, and Peri-prostatic block Group: Patients in which peri-prostatic block was given. Results: Mean pain score among the patients of Lidocaine gel group, Peri-anal block group, and Peri-prostatic block group was 3.96, 1.85 and 1.72 respectively. Significant results were obtained while comparing the mean score in between Lidocaine gel group and Peri-anal block group and in between Lidocaine gel group and Peri-prostatic block group. However; while comparing the mean pain score in between Peri-anal block group and Peri-prostatic group, non-significant results were obtained. Conclusion: Lidocaine gel is associated with little anaesthetic advantage to patients. Peri-prostatic nerve block and Peri-anal decreased pain significantly.