Journal of AdvancedMedical and Dental Sciences Research

Background: Hypothyroidism induces a decreased basal metabolism and thermogenesis, an accumulation of hyaluronic acid and a decreased renal flow. The present study was conducted to assess relation of thyroid function with body mass index in girls. Materials & Methods: 90 girls of age ranged 12-18 years were classified into group I and II based on normal and abnormal BMI level, respectively. Thyroid-stimulating hormone and total T4 were recorded by Cobas e411 based on electrochemiluminescence assay (ECLIA). Results: Age group 12-13 years had 35, 14-15 years had 28 and 16-18 years had 27 girls. The difference was non- significant (P> 0.05). The mean age in group I was 15.4 years and in group II was 19.0 years, height was 156.8 cm in group I and 158.2 cm in group II, weight was 46.2 kg in group I and 50.1 kg in group II, BMI was 20.5 Kg/m2 in group I and 25.1 Kg/m2 in group II, TSH level was 2.7 μIU/mL in group I and 3.9 μIU/mL in group II and total T4 in group I was 10.3 ng/dL in group I and 9.8 ng/dL in group II. The difference was significant (P< 0.05). Conclusion: Subjected with higher BMI had higher level of TSH. Thus there is association between high BMI and thyroid level.