Journal of AdvancedMedical and Dental Sciences Research

Background and Objective:- The present study was conducted with the aim to evaluate the effect of local anesthesia with adrenaline as compared to local anesthesia without adrenaline on blood glucose level in diabetic patients. Materials and Methods:- This randomized prospective study consisted of 100 patients. The age of the patients were between 20 to 70 years, irrespective of sex. All patients were having controlled type-2 diabetes mellitus, requiring multiple extractions to be performed. The study was carried out in two appointments, where in the first appointment tooth extraction was carried out under plain local anesthesia (Group A) and after 5 to 7 days, remaining extractions were carried out under local anesthesia with adrenaline (Group B). Serial blood glucose estimations were carried out at identical intervals on both occasions. Results:- The mean increase of blood glucose level in patients with plain local anesthesia was 0.15, 0.09 and 0.08 mg/dl while those in patients with local anesthesia plus adrenaline was 7.07, 23.22 and 36.83 mg/dl respectively immediately after injecting, after 10 mins and after 20 mins respectively. Conclusion:- The use of local anesthetic with adrenaline produces a significant increase in blood glucose level among controlled diabetic subjects. Keywords: Local anesthesia, adrenaline, type-2 diabetes mellitus, blood glucose level