Journal of AdvancedMedical and Dental Sciences Research

Background: Inflammatory Bowel disease (IBD) is a perplexing disease characterized by chronic mucosal inflammation. It results from a complex interplay of various factors including genetic and environmental, and adaptive immunity of the host. The present study was conducted to assess cases of inflammatory bowel disease (IBD) among children. Materials & Methods: 52 children diagnosed with inflammatory bowel disease of both genders were recruited. Etiology, clinical features and management of cases was recorded. Results: Common clinical features among crohn’s disease (CD) and ulcerative colitis (UC) were abdominal pain in 15 and 20, diarrhoea in 20 and 12, fever in 11 and 9, weight loss in 6 and 4, perianal disease in 4 and 2 and hematochezia in 8 and 7 patients respectively. Erythema nodosum was present in 6, pyoderma gangrenosum in 2, arthritis in 1, osteoporosis in 5, uveitis in 2, anemia in 3 and autoimmune hepatitis in 1 case. The difference was significant (P< 0.05). Conclusion: Common clinical features were abdominal pain, diarrhoea, fever, weight loss, perianal disease and hematochezia. Key words: Crohn’s disease, Inflammatory Bowel disease, Ulcerative colitis.