Journal of AdvancedMedical and Dental Sciences Research

Background: Spinal anaesthesia is the method of choice for caesarean section, especially in case of elective procedures. The present study was conducted to compare intravenous norepinephrine and mephentermine for maintenance of blood pressure during spinal anaesthesia for caesarean section. Materials & Methods: 94 parturients posted for elective caesarean section (CS) under SAB (subarachnoid block) were randomly divided into 2 groups of 47 each. Group I received boluses of intravenous norepinephrine 8 µg and group II received mephentermine 6 mg for SAIH. Results: The number of requirement of doses were 1 time seen in 4 in group I and 18 in group II, 2 times seen 10 in group I and 13 in group II, 3 times seen 16 in group I and 10 in group II, 4 times seen 9 in group I and 6 in group II, 5 times seen 5 in group I and 6 times seen 3 in group I. The difference was significant (P< 0.05). A non- significant difference was observed in change in systolic and diastolic blood pressure in both groups (P> 0.05). Conclusion: Intravenous norepinephrine was comparable with mephentermine in maintenance of blood pressure. Key words: Blood pressure, Mephentermine, Norepinephrine