Journal of AdvancedMedical and Dental Sciences Research

Background: Diabetes (T2DM) and related cardiovascular complications are major public health challenges worldwide. The present study was conducted to assess hypercholesterolemia and retinopathy in prediabetes. Materials & Methods: 120 pre- diabetic and diabetic subjects underwent fasting serum lipids (total cholesterol, T-Chol; triglycerides, Tg; low density lipoprotein cholesterol, LDL-C and high-density lipoprotein cholesterol, HDL-C). Results: Out of 120 subjects, males were 70 and females were 50. The mean cholesterol (mmol/L) in healthy, pre- diabetics and diabetics was 4.1, 4.5 and 4.9, triglyceride (mmol/L) was 1.1, 1.5 and 1.8, HDL (mmol/L) was 0.90, 0.84 and 0.80, LDL (mmol/L) was 2.74, 2.80 and 2.86 respectively. There was correlation of cholesterol, triglyceride in pre-diabetic and diabetic (P< 0.05). 34 (28.3%) had diabetic retinopathy. Conclusion: There was a high lipid profile in pre-diabetics and diabetics. The prevalence of diabetic retinopathy was also high. Key words: Diabetic retinopathy, Lipid, Cholesterol