Journal of AdvancedMedical and Dental Sciences Research

Background: The present study was conducted to assess antibacterial and antifungal efficacy of platelet-rich fibrin (PRF) and platelet-rich fibrin matrix against root canal microflora. Materials & Methods: The present study was conducted on 36 subjects of both genders. Blood samples were obtained from all subjects, PRF (group I) and PRFM (group II) were processed as per the protocol. The susceptibility test against microbiota in the root canal and Candida albicans was assessed through minimum inhibition zone by agar diffusion technique. Results: The mean antibacterial scores in group I was 4.16 and in group II was 1.20. The difference was significant (P< 0.05). The mean antifungal scores in group I was 1.72 and in group II was 0.46. The difference was significant (P< 0.05). Conclusion: Authors found that the antibacterial efficacy of PRF may prove beneficial as compared to PRF matrix. Key words: Antifungal scores, Antibacterial scores, Platelet-rich fibrin.