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Volume 7 Issue 12 (December, 2019)

Original Articles

Etiologic, Clinical profile and outcome of patients with severe acute pancreatitis in a tertiary care hospital
Abhinav Mittal

Background: Acute pancreatitis is a complex condition with diverse local and systemic complications, dealt by the surgeons all over the world. The present study was conducted to study the clinical profile and outcome of patients with severe acute pancreatitis. Materials & Methods: The study was conducted on 80 patients of acute pancreatitis. Clinical profile including history, examination findings, etiology of pancreatitis, clinical severity (according to Modified Marshall Score , BISAP score, APACHE II, HAPS score, SOFA score) was recorded. Results: 80 patients 54 (67.5%) patients were in the age group of 18-40 years, 18 (22.5%) patients were in 40-60 years group while 8 (10%) were aged > 60 years. Mean age of patients was 40.6 ± 12.8 years. Majority of the patients were male 32 (80%) and female were only 8 (20%). Majority of the patients i.e. 44 (55%) had alcohol consumption as etiological factor causing SAP followed by biliary 20 (25%) & idiopathic 10 (12.5%). Hypertriglyceridemia and drug induced (herbal medication) pancreatitis was present in 2 (2.5%) patient each. Out of all 2 (2.5%) patient had history of both alcohol consumption and presence of gall stone as etiological factor. Patients who improved had mean BISAP SCORE of 2.25 ± 0.42, Modified Marshall score of 3.46 ± 1.26, APACHE II score of 8.56 ± 4.45, SOFA score 6.54 ± 2.49, RANSON's score 6.85 ± 0.60 and HAP score of 0.56 ± 0.46. Conclusion: Acute pancreatitis is one of the leading causes for increase morbidity and mortality to society. Most common etiology of severe acute pancreatitis is alcohol followed by biliary etiology. Clinical assessment along with lab markers correlated well with the mortality and morbidity. Multiple organ failure, ICU admission and mortality are higher in pancreatitis present with necrosis. Key words: Acute pancreatitis, APACHE II, Severity scores.

 
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