Journal of AdvancedMedical and Dental Sciences Research

Introduction: Papulosquamous diseases are a heterogeneous group of disorders which assume considerable importance because of their frequency of occurrence. The interpretation of many skin biopsies requires the identification and integration of two different morphological features- the tissue reaction pattern and the pattern of inflammation. Aim: To study the histomorphology of papulosquamous lesions of skin with clinico-pathological correlation. Material and methods: This present study included 100 cases presenting with clinical features papulosquamous skin disorders were included in the study, irrespective of age and sex History and clinical examination of each patient was recorded on a self designed proforma. Final diagnosis was made on the basis of the histopathological findings. Results: Mean age observed was 42.2 years, with maximum number of cases in the age group 31-40 years. Male predominance was observed with Male: Female ratio of 1.5:1. Predominant lesion was Psoriasis(60%) fllowed by lichen planus (24%). While others were Pityriasis Rubra Pilaris with 5 cases (5%), lichen planus pigmentosum with 4 cases (4%), Parasoriasis with 3 cases (3 %), Pityriasis rosea with 2 cases (2 %), seborrheic dermatitis 2 cases (2%). Overall a positive Correlation with the histopathological diagnosis was positive in 89% cases and negative in 11% cases. Conclusion: Most of these papulosquamous skin lesions have a similar clinical presentation characterized by scaling papules or plaques. Hence combination of proper clinical observation and histo morphological study will give a conclusive diagnosis. Key words: Clinicopathological correlation, Histopathological features, Papulosquamous lesions, Psoriasis, Lichen planus.