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Volume 4 Issue 4 (July - August, 2016)

Original Articles

Assessment of HbA1c concentrations among diabetic patients with and without diabetic complication- A Biochemical Study
Shakti Agarwal, Parul Chandra

Background: Diabetes mellitus (DM) is a chronic disease of hyperglycemia associated with metabolic syndrome, which is characterized by insulin resistance. Diabetic foot complications are contributing to both mortality and morbidity among the diabetic population leading to substantial physical, physiological and financial burden for the patients and community at large. Hence; the present study was planned for assessing and coring the HbA1c concentrations among diabetic patients with and without diabetic complication. Materials & methods: A total of 25 diabetic patients with diabetic foot complication and 25 diabetic patients without diabetic foot complication were enrolled in the present study. Complete clinical examination of all patients was carried out. Blood samples were obtained from all the patients and mean HbA1c concentration was analysed and compared. Results: Mean HbA1c concentration among patients with and without diabetic foot complication was 8.75% and 10.19% respectively. Mean FBS concentration among patients with and without diabetic foot complication was 101.9mg/dL and 114.3mg/dL respectively. Mean RBS concentration among patients with and without diabetic foot complication was 119.4mg/dL and 129.5 mg/dL respectively. Mean HbA1c, FBS and RBS concentrations among the patients with diabetic foot complication was significantly higher among the patients without diabetic foot complication. Conclusion: HbA1c levels are significantly altered in patients with diabetic foot complications. Key words: Diabetic foot complication, HbA1c

 
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