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Volume 7 Issue 7 (July, 2019)

Original Articles

Assessment of Serum Lipid Profile in Patients with Oral Submucous Fibrosis and Oral Squamous Cell Carcinoma- An in-vivo study
Rajiv Puri

Background:  Biochemical studies in evaluation of cancer have shown that various substances alter quantitatively in the serum during tumor development and are referred to as tumor markers. Hence; the present study was planned for assessing the serum lipid profile in patients with oral submucous fibrosis (OSMF) and oral squamous cell carcinoma (OSCC). Materials & methods: A total of 60 subjects were included in the present study. Among these 60 subjects, 20 subjects were of OSCC, 20 subjects with OSMF and 20 healthy controls. A self-framed questionnaire was framed for assessing the clinical and demographic details of all the subjects. Blood samples were taken from all the patients and were sent to laboratory for assessment of serum lipid profile. In the laboratory, auto-analyzer was used for assessment. Compilation of all the results were done in Microsoft excel sheet and were analyzed by SPSS software. Results: Significant results were obtained while comparing mean serum lipid profile among OSMF patients, OSCC patients and normal controls.  Conclusion: Mean serum lipid profile is significantly altered in OSMF and OSCC patients. However; further studies are recommended.
Key words: Lipid, Oral submucous fibrosis Premalignant

Received: 13 March, 2019                                         Revised:  22 April 2019                             Accepted: 25 April 2019
                        
Corresponding author: Dr. Rajiv Puri, B.D.S., M.D.S., Graded Specialist (Oral & Maxillofacial Pathology), Army Dental Corps, India
               
This article may be cited as: Puri R. Assessment of Serum Lipid Profile in Patients with Oral Submucous Fibrosis and Oral Squamous Cell Carcinoma: An in-vivo study. J Adv Med Dent Scie Res 2019;7(7): 168-170.

 
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