Journal of AdvancedMedical and Dental Sciences Research

Background: Early pregnancy failure (EPF) is a common event in human pregnancy, accounting for 10–20% of recognized pregnancies. The present study was conducted to determine association of serum hCG level with Early pregnancy failure. Materials & Methods: The present study was conducted on 228 asymptomatic pregnant women with a gestation of 6 to 16 weeks reported to the department. Patients were followed upto 20 weeks or EPF was diagnosed by ultrasound scanning.  Measurement of serum HCG was performed using the Siemens Immulite 2000 and results were expressed as mIU/ml. Mean hCG level in women with EPF <10 days was 40225.2 mIU/ml. Women with EPF 10-20 days was 44682.7. The mean hCG level in women with EPF >20 days was 65327.8. The mean hCG level in women without EPF was 92114.5. The difference was significant (P< 0.05). Results: The mean hCG in women with EPF was 451563.4 mIU/ml and in women without EPF was 92144.5 mIU/ml. The difference was significant (P< 0.05). We observed that mean hCG level in women with EPF <10 days was 40225.2 mIU/ml. Women with EPF 10-20 days was 44682.7. The mean hCG level in women with EPF >20 days was 65327.8. The mean hCG level in women without EPF was 92114.5. The difference was significant (P< 0.05). Conclusion: There was low level of hCG in women with EPF than women without EPF.
Key words: Early pregnancy failure, hCG, Women, EPF.

Received: 24 March, 2019                                         Revised:  28 April, 2019                            Accepted: 29 April, 2019

Corresponding Author: Dr. Mridula Sharma, Department of Obstetrics & Gynaecology, Rajshree Medical Research Institute, Bareilly, Uttar Pradesh, India

This article may be cited as: Agarwal K, Sharma M. Evaluation of Association of Serum Human Chorionic Gonadotrophin level with Early Pregnancy Failure. J Adv Med Dent Scie Res 2019;7(7): 152-155.