Journal of AdvancedMedical and Dental Sciences Research

Background: Saliva is a complex fluid in the oral cavity, composed of a mixture of secretary products from the major and minor salivary glands. Uric acid has been considered as the major antioxidant present in human saliva. Hence; we planned the present study to assess the salivary uric acid levels in patients with dental caries. Materials & methods: A total of 50 patients with clinical evidence of dental caries were included in the present study. Another set of 50 subjects with absence of clinical evidence of dental caries along with absence of any sign and symptom indicative of dental caries were included as healthy controls. Salivary samples were taken from all the subjects and were sent to laboratory for assessment of salivary uric acid levels. Results: Mean salivary uric acid levels among the subjects of the study group and control group was 2.22 and 2.35 mg/dl respectively. Non- significant results were obtained while comparing the mean salivary uric acid levels among subjects of the study group and the control group. Conclusion: Alteration in uric acid levels might occur in patients with dental caries thus highlighting the role of antioxidant system in the pathogenesis of the disease.
Key words: Dental caries, Uric acid.

Received: 8 March, 2019                                 Revised: 27 March, 2019                               Accepted: 28 March, 2019

Corresponding Author: Dr. Deepak Narang, PG teacher Oral Medicine, Prasad Medical College, Lucknow, U.P., India

This article may be cited as: Narang D, Jain A. Estimation of salivary uric acid in dental caries: A biochemical study. J Adv Med Dent Scie Res 2019;7(4): 106-108.