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Volume 3 Issue 1 (January - March, 2015)

Original Articles

IMPACT OF CLINICAL HISTORY ON HISTOPATHOLOGIC GRADING IN ORAL EPITHELIAL DYSPLASIA
Adesh S Manchanda, Aalamdeep Kaur, Jyotika Goel, Dilawarjit Kaur, Japneet Kaur, Gurbinder S Kang

1Department of Oral & Maxillofacial Pathology, Sri Guru Ram Das Institute of Dental sciences & Research, Amritsar, 2B.D.S

Objective: To compare the grade of oral epithelial dysplasia (sign out diagnosis) with the clinical history of the patient and subjects habit duration if any. Study design: 45 histologic sections of oral epithelial dysplasia, 15 each of mild, moderate and severe dysplasia (sign out diagnosis) based on WHO classification system were selected. The sections were of acceptable diagnostic quality, were from an intra-oral site and included referral information on age, sex and site of the lesion and habit history if any as clinical details for a sign out diagnosis. Result: Of the 45 histologic sections, a male predilection was noticed in all the grades of dysplasia; but it could not be taken as a clinical parameter to decide the grade of dysplasia as no statistical significance was found. An insignificant relation was seen between site and grade of dysplasia (P= 0.077). The age of individual and his/her habit duration of smoking; chewing tobacco and alcohol respectively were correlated and found to be important with a significant P value of 0.000, 0.099, 0.033 and 0.024 respectively. Conclusion: Grading of lesions of oral epithelial dysplasia, keeping in view the clinical features needs to be precise and accurate with respect to the overall prediction of disease progression.

Corresponding Author: Dr. Adesh S Manchanda, MDS, Senior Lecturer, Department of Oral & Maxillofacial Pathology, Sri Guru Ram Das Institute of Dental sciences & Research, Amritsar, GT Road Punjab, India. Email:  adesh_manchanda@yahoo.com

This article may be cited as: Manchanda AS, Kaur A, Goel J, Kaur D, Kaur J, Kang GS.  Impact of Clinical History on Histopathologic Grading in Oral Epithelial Dysplasia. J Adv Med Dent Scie Res 2015;3(1):26-32.

 
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