Background: Penicillin and amoxicillin are the antibiotics of choice for the treatment of pharyngitis. The association of amoxicillin and clavulanate is not indicated as the initial treatment of acute infection. Neither are macrolides indicated as first-line therapy; they should be reserved for patients allergic to penicillin. Hence; we planned the present study to assess the efficacy of Clarithromycin and Penicillin V in treating pharyngitis patients. Materials & methods: The present study included evaluation and comparison of efficacy of Clarithromycin and Penicillin V in treating pharyngitis patients. A total of 40 patients diagnosed with suffering from streptococcal pharyngitis were included in the present study and were broadly divided into two study group; Group A included patients who were given Clarithromycin therapy, while Group B included patients who were given Penicillin V therapy. Both clinical and microbiological methods were used for assessing the efficacy of both the drugs. All the results were analysed by SPSS software. Results: Sore throat and erythema were the most common initial signs and symptoms observed. Complete clinical cure was observed in 15 and 16 cases of group A and group B respectively. Complete bacteriological cure was observed in 15 patients each of both the study groups respectively. Conclusion: Both the drugs are of equal efficacy in treating patients with pharyngitis.
Key words: Pharyngitis, Treatment