Journal of AdvancedMedical and Dental Sciences Research

Background:Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by high blood sugar levels (hyperglycemia) resulting from insulin resistance and relative insulin deficiency. The present study was conducted to assess clinical and biochemical profiles of lean type 2 diabetes mellitus (T2DM) patients. Materials & Methods:84 type 2 diabetes mellitus patients with BMI less than 19 of both genders were selected. Anthropometric parameters – height, weight, waist, hip circumference, and waist-hip ratio, fasting and two hours postprandial blood glucose (BG) and HbA1c (glycosylated haemoglobin), lipid profile such as TG, HDL, LDL, TC, and VLDL were measured. Results: Out of 84 patients, males were 52 and females were 32. In males and females, mean height (cm) was 165.8 and 151.3, weight (kg) was 50.2 and 42.9, BMI (kg/m2) was 16.7 and 18.4, WC (cm) was 76.4 and 71.2, HC (cm) was 82.5 and 81.3, waist-hip ratio was 0.97 and 0.87, SBP (mm Hg) was 128.4 and 126.2, and DBP (mm Hg) was 76.2 and 74.8 respectively. The difference was significant (P< 0.05). The mean fasting BG (mg%) was 134.8, postprandial BG (mg%) was 201.4, HbA1c (%) was 7.6, TC (mg%) was 186.2, TG (mg%) was 145.2, LDL (mg%) was 108.4, HDL (mg%) was 49.2, and VLDL (mg%) was 32.6. Conclusion: Lean people with type 2 diabetes mellitus (T2DM) hasdyslipidemia, making the condition a unique clinical entity.