Journal of AdvancedMedical and Dental Sciences Research

Background: Obesity and Type 2 diabetes (T2DM) together are becoming a fatal mix. While the precise causes of T2DM are still mostly unknown, a number of factors are thought to be involved. The present study evaluated correlation between obesity and glycated hemoglobin in type II diabetes patients. Materials & Methods: 110 type II diabetes mellitus patients of both genders were divided into two categories: Normal BMI (18.0–22.9 kg/m2), Overweight (23.0–24.9 kg/m2), and Obesity (>25 kg/m2). Glucose oxidase was used to measure fasting plasma glucose, and Latex agglutination inhibition assay was used to measure HbA1c. Results: Out of 110 patients, males were 68 and females were 42. There were 34 patients with BMI between 18.5-25 kg/m2, 30 with 25-30 kg/m2 and 46 with 25-30 kg/m2 BMI. The difference was significant (P< 0.05). The mean FBG was 152.4 mg/dl, 147.6 mg/dl and 170.2 mg/dl, SBP was 138.4 mm Hg, 129.4 mm Hg and 134.6 mm Hg, DBP was 90.2 mm Hg, 74.2 mm Hg and 82.2 mm Hg, WC was 82.4 cm, 96.5 cm and 101.3 cm and HbA1C was 6.1%, 8.4 % and 8.7% in normal, overweight and obese patients respectively. The difference was significant (P< 0.05). Conclusion: The prevalence of obesity was greater in persons with diabetes. Among diabetes subjects with medium BMI who were also overweight or obese, dysglycemia was elevated.