Journal of AdvancedMedical and Dental Sciences Research

Background: This study was conducted to assess the histopathological features of abnormal uterine bleeding (AUB). Material and methods: A total of 100 patients diagnosed with AUB were enrolled. Complete demographic and clinical details of all the patients was obtained. Endometrial biopsy specimens were obtained. All specimens were transported in 10% formalin to the pathology laboratory. The gross morphology was recorded and the tissue bits were processed and paraffin blocks were prepared. Sectioning of the tissue sections was done and were stained with hematoxylin and eosin stain (H&E). Results: Normal cylindrical pattern was seen in 26 percent of the patients. Disordered proliferative pattern was seen in 22 percent of the patients. Hyperplasia and atrophic pattern were observed in 17 percent and 10 percent of the patients. Benign endometrial polyp and endometrial carcinoma was seen in 20 percent and 5 percent of the patients respectively. While correlating the age-wise distribution of patients with endometrial findings, non-significant results were obtained. Conclusion: Histopathological examination of endometrial biopsy is a major diagnostic tool in evaluation of AUB.