Journal of AdvancedMedical and Dental Sciences Research

Background:Psoriasis is linked to notable morbidity, potentially exerting a considerable influence on patients' quality of life, even when affecting a relatively small body surface area. The objective of this study was to examine the correlation between psoriasis and metabolic syndrome. Additionally, the research aimed to assess the disease activity and duration in psoriatic patients, comparing those with and without metabolic syndrome.Methods:The study incorporated 170 subjects with psoriasis who had not undergone systemic treatment in the preceding two months. Comprehensive assessments, including a full lipid profile, fasting blood glucose levels, blood pressure measurements, and an evaluation of central obesity, were conducted to formulate the results.Results:Among the 170 patients, 66 were found to have metabolic syndrome. Notably, 60% exhibited impaired HDL levels, and 55.2% showed fasting triglyceride abnormalities within the metabolic syndrome group. The study revealed a direct association between metabolic syndrome and the extent of body surface area affected by psoriasis. Patients with psoriasis lasting over 70 months demonstrated a higher prevalence of metabolic syndrome, accounting for 37.84%. Interestingly, no significant correlation was observed between the Psoriasis Area and Severity Index (PASI) score and the presence of metabolic syndrome.Conclusion:In summary, the current study establishes a clear association between psoriasis and metabolic syndrome. This finding holds significant implications within the field of dermatology, emphasizing the need to address and manage this correlation to prevent potential serious complications.