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Volume 5 Issue 3 (March, 2017)

Original Articles

Evaluation of cutaneous adverse drug reactions
Shashi Ranjan

Background: Cutaneous adverse drug reactions are adverse skin reactions caused by medications. The present study was conducted to assess cutaneous adverse drug reactions. Materials & Methods: 94 cases of suspected CADRs presented with the use of FDCs were recorded. The causality assessment was carried out using the WHO UMC scale. The severity of these CADRs was assessed by Hartwig scale. The ADRs were also analyzed by modified Schumock and Thornton Criteria. Results: Cutaneous adverse drug reactions found to be MPDR in 15%, FDE in 42%, SJS- TENS in 13%, erythroderma in 8% and rash in 22%. The difference was significant (P< 0.05).Cutaneous adverse drug reactions were due to prescribed by practitioners in 32% and self-medication in 68% cases. The difference was significant (P< 0.05). Conclusion: Most of the adverse drug reactions were due to self-medication. A sound knowledge of the adverse drugs reactions, a careful history taking and a cautious approach during the prescription of new drugs can prevent most of these adverse drug reactions.

 
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