Journal of AdvancedMedical and Dental Sciences Research

Background: Undergoing transjugular intrahepatic portosystemic shunt (TIPS) procedures and liver transplantation (LT). The specific objectives were to assess the frequency of cardiac abnormalities, such as diastolic dysfunction, systolic dysfunction, and arrhythmias, in this patient population, and to investigate potential risk factors associated with these cardiac issues. The study also sought to evaluate the impact of pre-existing cardiac dysfunction on postoperative outcomes and mortality in chronic liver disease patients undergoing TIPS and LT. Methods: Furthermore, the study gathered relevant clinical and demographic information from these patients. Physical examinations were conducted to assess their overall health. Cardiological evaluations included electrocardiograms (ECG) and two-dimensional echocardiograms (2D ECHO) to detect cardiac abnormalities. Blood investigations were performed to obtain relevant health data and identify potential risk factors. Results: The study found notable differences in the mean age of patients with and without cardiac dysfunction, with those experiencing cardiac dysfunction having a higher mean age (46.15 years) compared to those without (40.2 years). Cardiac dysfunctions in chronic liver disease (CLD) patients were predominantly observed in the age group of 51-60 years, and a significant majority (95%) of these cases were male, while only a small percentage (5%) were female. The study also revealed a prevalence of diastolic dysfunction in 24% of CLD patients, and systolic dysfunction was prevalent in 20% of the same patient population. Conclusion: The study underscores a critical concern regarding subclinical cardiac dysfunctions found in a substantial number of chronic liver disease (CLD) patients. These subclinical dysfunctions have significant implications, particularly when these patients undergo surgical procedures like transjugular intrahepatic portosystemic shunt (TIPS) or liver transplantation.