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Volume 6 Issue 5 (May, 2018)

Original Articles

To evaluate the efficacy of epidural levobupivacaine 0.75% against racemic bupivacaine in patients undergoing lower abdominal surgery
Manish Kumar, Himanshu Yadav

Aim: The purpose of this study is to evaluate the efficacy of epidural levobupivacaine 0.75% against racemic bupivacaine in patients undergoing lower abdominal surgery. Materials and Methods: Epidural Levobupivacaine 0.75% and Racemic Bupivacaine were compared in the current prospective trial for lower abdominal surgery. Before the research began, ethical permission was obtained from the institute's ethics committee, and the patient's signed agreement was obtained after being informed about the investigation. The research comprised 20–65-year-old patients with ASA physical status I–II who were scheduled to have elective lower abdomen surgery under epidural anaesthesia. Results: 100 patients in all were participated in the trial, and they were split into two groups before receiving double-blind anaesthesia. Levobupivacaine was in group A, while buprenorphine was in group B. The average time it took for levobupivacaine and bupivacaine groups to reach a level of sensory block sufficient for surgery (T10) was 14.01 minutes and 15.02 minutes, respectively. T 6.99 dermatone was the maximum spread for group A, while T 7.69 dermatone was the maximum spread for group B. For group A, it took 26.58 minutes, while for group B, it took 27.85 minutes to reach the maximum spread. Regression to T10 took 382.55 minutes in group A and 361.58 minutes in group B. In groups A and B, full regression took 549.89 and 506.96 minutes, respectively. Group A's anaesthesia lasted for 371.22 minutes, whereas group B did so for 333.25 minutes. Conclusion: According to the findings of this research, the sensory and motor block that is induced by 0.75% levobupivacaine is equal to that which is created by 0.75% racemic bupivacaine.

 
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