Journal of AdvancedMedical and Dental Sciences Research

Background: Middle ear surgery under general anaesthesia is revolutionised with the introduction of hypotensive anaesthesia. The present study evaluated the role of dexmedetomidine infusion as anaesthetic adjuvant during middle ear surgery. Materials & Methods: 80 adult patients scheduledfor elective middle ear surgery were divided into 2 groups. Group I patients received infusion of dexmedetomidine 0.5 µg/kg/hour and group II patients received placebo infusion of normal saline during middle ear surgery after induction of anaesthesia till 20 minutes before completion of surgery. All patients were assessed intra operatively for bleeding at surgical field and haemodynamic changes. Results: Group I had 16 males and 24 females and group II had 20 males and 20 females. The mean surgical time in group I was 95.2 minutes and in group II was 102.4 minutes, mean percentage of isoflurane requirement of 0.82% in group I and 1.50 % in group II heart rate (beats/min) was at baseline in group I was 93.1 and in group II was 93.8, after induction was 72.3 in group I and 73.0 in group II, after intubation 5 min was 71.6 in group I and 76.4 in group II, 30 min was 70.6 in group I and 77.8 in group II, at 60 min was 67.7 in group I and 86.2 in group II and after extubation was 83.5 in group I and 96.3 in group II. Conclusion: Dexmedetomidine infusion was safe to provide oligaemic surgical field for middle ear surgery.