Journal of AdvancedMedical and Dental Sciences Research

Background: Middle ear surgery under general anaesthesia is revolutionised with the introduction of hypotensive anaesthesia. The present study evaluated the role of dexmedetomidine infusion as anaesthetic adjuvant during middle ear surgery in children. Materials & Methods: 60 Pediatric patients aged ranged 12-17 yearsof both genders selected for elective middle ear surgery. Group I patients received infusion of dexmedetomidine 0.5 µg/kg/hour and group II patients received placebo infusion of normal saline during middle ear surgery after induction of anaesthesia till 20 minutes before completion of surgery. All patients were assessed intra operatively for bleeding at surgical field and haemodynamic changes. Results: Group I had 16 males and 14 females and group II had 13 males and 17 females. The mean surgical time in group I was 98.2 minutes and in group II was 102.4 minutes, heart rate was at baseline in group I was 95.1 beats/min and in group II was 93.8 beats/min, after induction was 72.3 beats/min in group I and 73.0 beats/min in group II, after intubation 5 min was 78.6 beats/min in group I and 76.4 beats/min in group II, 30 min was 74.6 beats/min in group I and 79.8 beats/min in group II, at 60 min was 70.7 beats/min in group I and 88.2 beats/min in group II and after extubation was 85.5 beats/min in group I and 96.3 beats/min in group II. The difference was significant (P< 0.05). There was mean percentage of isoflurane requirement of 0.87% in group I and 1.45 % in group II. The difference was significant (P< 0.05).Conclusion: Dexmedetomidine infusion provided oligaemic surgical field for better visualisation for middle ear surgeryunder operating microscope.