Journal of AdvancedMedical and Dental Sciences Research

Background: Propofol is becoming the intravenous anesthetic of choice for ambulatory surgery in outpatients. The present study compared efficacy of Ondansetron and Ramosetron in controlling propofol‑induced pain. Materials & Methods: 60 patients of both genders were divided into 2 groups of 30 each. Group I received 4 mg of Ondansetron and group II received 0.3 mg of Ramosetron. Pain was assessed with a four‑points scale. Results: There were 16 males and 14 females in group I and 15 males and 15 females in group II. Pain score 1 was seen in 5 in group I and 8 in group II, score 2 was seen in 9 in group I and 14 in group II, score 3 was seen in 12 in group I and 7 in group II and score 4 was seen in 4 in group I and 1 in group II. The difference was significant (P< 0.05). Conclusion: 0.3 mg of ramosetron found to be effective than 4 mg of ondansetron in controlling propofol induced pain.