Journal of AdvancedMedical and Dental Sciences Research

Background: To study the serum levels of interleukin-6 in plaque type psoriasis. Materials & methods: A total of 40 subjects were enrolled. The age of patients included was 30 to 60 years. Blood samples were collected and centrifuged. Serum samples were collected. Patients were off topical treatment for 4 weeks prior to the PASI score evaluation and blood sample collection. Serum levels with IL-6 were measured using ELISA kit. Result was analysed using SPSS software. The statistical significance was accepted when p < 0.05. Results: The cytokines investigated in this study were detected in serum samples from all patients whereas IL-6 were below the minimum detection level of the kit in healthy controls. Conclusion: Serum levels of IL-6 were not correlated with PASI.