Journal of AdvancedMedical and Dental Sciences Research

Aim: Evaluate the relationship between pregnancy serum lipid concentrations and risk of preeclampsia. Material and Methods: A cross sectional study was conducted in Department of Biochemistry, after taking the permission from the ethical committee. Total 300 patients include 100 non-pregnant,100 pregnant and 100 PIH cases. Serum cholesterol, lipoproteins and triglyceride levels were evaluated for each of the three groups. Results: In the present study there was no significant difference in serum cholesterol levels between group I (normal, non-pregnant women) and group II (normal pregnant women). However, a significant difference was observed between group I and group III (pregnancy with PIH) the P values being<0.001. The serum cholesterol levels in group III were significantly higher than those in group I. However, there was a significant difference in serum cholesterol levels between group II and group III. The P value being <0.001. Conclusion: Pregnancy induced hypertension is a frequent complication during pregnancy which if advanced may be fatal for both mother and foetus. Endothelial damage might involve elevated serum triglycerides which may have a value that can be used as screening markers in early stages of pregnancy leading to preeclampsia in future.