Journal of AdvancedMedical and Dental Sciences Research

Background: Type 2 diabetes is associated with dyslipidaemia comprising of multiple lipoprotein disorders. The present study was conducted to assess serum myeloperoxidase, apolipoprotein B and glycated hemoglobin levels in type 2 diabetes mellitus. Materials & Methods: 46type II DM patients of both genders were enrolled. 2 groups were formed. Group I had type II DM and group II had healthy control. 6ml of fasting venous blood samples is drawn under aseptic precautions in to a sterile bulb from selected subjects. The levels of serum myeloperoxidase (MPO), glycated hemoglobin (HbA1c) and apolipoprotein B was measured. Results: We found thatgroup I had 26 males and 20 females and group II had 22 males and 24 females.We found that mean serum Apo B was 236.1 mg/dl in group I and 125.2 mg/dl in group II, HbA1c level was 7.3% in group I and 4.0% in group II, mean MPO level was 21119 pg/ml in group I and 10136 pg/ml in group II. The difference was significant (P< 0.05). Conclusion: The level of serum myeloperoxidase (MPO), glycated hemoglobin (HbA1c) and apolipoprotein B was higly elevated in type II DM patients as compared to healthy control.