Journal of AdvancedMedical and Dental Sciences Research

Background: CKD leads to deterioration of renal function, which results from diminished effective functioning of renal tissues. The present study was conducted to assess the serum lipid profile in CKD patients. Materials & Methods: 60 CKD patients of both genders were kept in group I and equal age and gender matched healthy subjects in group II. Assessment of blood urea, serum creatinine, lipid profile: total cholesterol, triglycerides, HDLc, LDLc, VLDLc were performed. Results: There were 38 males and 22 female CKD patients. The mean total cholesterol was 130.2 mg/dl in group I and 145.2 mg/dl in group II, TG was 152.4 mg/dl in group I and 98.4 mg/dl in group II, HDLc was 32.5 mg/dl in group I and 46.3 mg/dl in group II, LDLcwas 62.1 mg/dl in group I and 78.4 mg/dl in group II, VLDLc was 31.4 mg/dl in group I and 19.4 mg/dl in group II. The mean blood urea was 124.1 mg/dl in group I and 28.4 mg/dl in group II. The mean serum creatinine was 6.5 mg/dl in group I and 0.92 mg/dl in group II. The difference was significant (P< 0.05). Conclusion: Increased triglycerides, increased VLDL and reduced HDL are responsible for increased cardiovascular complications in patients with CKD.