Journal of AdvancedMedical and Dental Sciences Research

Background: GDM can cause prenatal and maternal complications for women such as: preeclampsia, cesarean delivery. The present study was conducted to evaluate cases of gestational diabetes mellitus. Materials & Methods: 80 women with gestational diabetes mellitus were enrolled. Patients were treated either medical nutritional therapy (MNT) or combined insulin along with MNT. All women were asked to drink 75 g of anhydrous glucose dissolved in 300 mL of water over 5–10 min period. After 2 hours of glucose ingestion, blood glucose levels were measured using plasma calibrated glucometers. Results: There were 24 subjects in GDM with PE and 20 in GDM without PE in primi, 10 in GDM with PE and without PE in 2nd gravida, 4 in GDM with PE and 6 in GDM without PE in 3rd and 2 in GDM with PE and 4 in GDM without PE in 4th and above gravida. GDM with PE and GDM without PE had 1st hour OGTT of 198.2 mg/dl and 170.2 mg/dl, 2 hours OGTT was 170.4 mg/dl and 152.6 mg/dl, weight gain was 17.6 kilogram and 12.4 kilogram and HbA1c levels was 7.32% and 7.06% respectively. The difference was significant (P< 0.05). Conclusion: Early detection of gestational diabetes with good antenatal care and strict glycemic control may decrease the chances of preeclampsia.