Journal of AdvancedMedical and Dental Sciences Research

Background: Iron deficiency (ID) is the most common nutritional disorder worldwide and affects millions of infants and children. The present study was conducted to assess thyroid function in children with iron deficiency anemia. Materials & Methods: 84 child patients age ranged 4-15 years of both genders were included. Group I comprised of children with ID anemia and group II had control. Complete blood count, thyroid profile, ferritin, iron, Total Iron Binding Capacity (TIBC), Transferrin Saturation% (TFS%), unsaturated iron binding capacity and Urinary Iodine Excretion (UIE) were assessed. Thyroid profile and ferritin were measured using commercially available Enzyme Linked Immunosorbent Assay (ELISA) kits; Results: The mean hemoglobin (gm/dl) was 9.4 and 11.2, MCV (fl) was 61.3 and 78.4, MCH (pg) was 22.1and 27.9, RDW (%) was 16.5 and 14.2, ferritin (ng/mL) was 12.3 and 45.3, iron concentration (µg/dL) was 20.5 and 91.2, total iron binding capacity (TIBC) (µg/dL) was 480.2 and 314.7 in group I and group II respectively. The mean TSH (µIU/mL) was 4.31 and 0.78, free T3 (pg/mL) was 1.1 and 4.2 and free T4 (ng/dL) was 0.91 and 1.34 in group I and group II respectively. The difference was significant (P< 0.05). Conclusion: Primary hypothyroidism can occur among children suffering from iron deficiency anemia.