Journal of AdvancedMedical and Dental Sciences Research

Background: AMI is one of the most common causes of morbidity and mortality in the industrialised world, and is becoming increasingly common in India as well. The present study was conducted to assess serum ferritin level in patients with acute myocardial infarction. Materials & Methods: of 80 patients of coronary heart disease of both genders (Group I) and age and sex-matched controls were selected (Group II). Serum ferritin was measured by enzyme-linked immunosorbent assay (ELISA) test. Results: The mean hemoglobin in group I was 12.1 gm% and in group II was 12.9 gm%, Ferritin level in group I was 280.4 µg/l and in group II was 98.2 µg/l, cholesterol level was 190.2 mg/dl and in group II was 86.4 mg/dl, HDL was 38.5 mg/dl in group I and 44.1 mg/dl in group II, LDL level was 116.4 mg/dl in group I and 86.2 mg/dl in group II, TG was 164.2 mg/dl in group I and 132.4 mg/dl in group II and VLDL was 33.5 mg/dl in group I and 27.2 mg/dl in group II. The risk factors for AMI was diabetes in 63 and 12, hypertension in 65 and 15, smoking in 52 and 6, BMI >25 kg/m2 in 48 and 14, cholesterol >200 mg/dl in 52 and 20, HDL < 35 mg/dl in 50 and 12, LDL >150 mg/dl in 68 and 5, TG >160 mg/dl in 72 and 3 and VLDL >40 mg/dl in 61 and 18 in group I and II respectively. The difference was significant (P< 0.05). Conclusion: Measurement of serum ferritin may be used as a complementary tool for confirming the diagnosis of AMI.