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Volume 8 Issue 12 (December, 2020)

Original Articles

A study of clinical profile of acute kidney injury in acute febrile illness
Dr. Hemant Ashok Edge, Dr. Abhijit A Nikam, Dr. Madhulika L Mahashabde, Dr. Gaurav Chaudhary, Dr. Drawpathy S

Background: Acute Febrile Illness (AFI) is defined as all acute febrile syndromes with oral temperature over 37.5℃ which last from 24 hours to less than two weeks, including nonspecific symptoms that are not helpful for us to localize to a particular system. Acute kidney injury (AKI) is defined as heterogenous syndrome of sudden decline in glomerular filtration rate (GFR) culminating into retention of metabolic waste products like urea and creatinine along with dysregulation of electrolytes and fluid and changes in acid base homeostasis. Hence; the present study was undertaken for assessing the clinical profile of acute kidney injury in acute febrile illness. Materials & methods: A total of 100 patients of acute febrile illness admitted in all medical wards and MICU were selected for the study. The diagnoses were made as per the standard diagnostic criteria. Detailed history of all participants was taken which included past, personal, medication and addiction history. Detail evaluation of all symptoms like fever, body ache, rash and other non-specific symptoms. Complete demographic and clinical profile was evaluated. Blood samples were obtained and complete biochemical profile was analysed. All the results were recorded in Microsoft excel sheet and were analysed by SPSS software. Results: The male to female ratio is 6.1:1. 2 (2.0) participants had mild hepatomegaly, 6 (6.0) participants had mild splenomegaly, 6 (6.0) participants had mild hepato-splenomegaly and 86 (86.0) participants had normal USG findings. 60 (60.0) participants were in Normal Grade, 17 (17.0) participants were in Risk Grade. Haemodialysis was required in 4 normal participants, 1 participant in Grade 2 group and 2 participants in Grade 3 group. Conclusion: Acute Kidney injury in Acute Febrile Illness is common in tertiary care hospital. Adults are at more risk for Acute Kidney injury. Dengue, Malaria, Leptospirosis and Enteric fever are among most common causes of acute febrile illness. Key words: Acute kidney injury, Febrile, Illness

 
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